The target compound IV (C₂₀H₂₁N) was synthesized through four-step reactions and structurally determined by single-crystal X-ray diffraction. The crystal of compound IV is in the orthorhombic system, space group Fdd2 with a = 41.178(19), b = 30.389(8), c = 4.8182(17) Å, β = 90°, C₂₀H₂₁N, M_r = 275.38, D_c = 1.213 g/cm³, V = 6029(4) ų, Z = 16, F(000) = 2368, µ(MoKa) = 0.527 mm^-1, T = 240(2) K, 2200 independent reflections with 1233 observed ones (I > 2σ(I)), R = 0.1285 and wR = 0.2589 with GOF = 1.050 (R = 0.2058 and wR = 0.3055 for all data). A one-dimensional interaction model of the title compound was formed by one kind of π-π interactions between the two phenyl rings of the adjacent molecules at upper and lower levels. The inhibition to the strand transfer process of HIV-1 integrase of the target compound was also evaluated.