One-dimensional (1D) chiral chain complexes [CuLSCu(Pydc)] (2S) and [CuLRCu(Pydc)] (2R) (LS = (E)-3-(((1S,2S)-2-(((E)-3-oxo-3-(4-pyridin-4-yl)phenyl)propylidene)amono)-1,2-diphenyl)imino)-1-(4-(py- ridi-4-yl)phenyl)butan-1-one) and LR = (E)-3-(((1R,2R)-2-(((E)-3-oxo-3-(4-pyridin-4-yl)phenyl)propyli- dene)amono)-1,2-diphenyl)imino)-1-(4-(pyridi-4-yl)phenyl)butan-1-one and Pydc = 2,6-pyridinedicarboxylic acid) have been synthesized vis mononuclear chiral enantiomer precursors CuLS (1S) and CuLR (1R). Their different chiral configurations of 1S, 1R, 2S and 2R were determined by single-crystal X-ray diffraction analyses and further characterized by elemental analyses, infrared spectra (IR), powder X-ray diffraction (PXRD), thermal gravimetric analyses (TGA) and circular dichroism spectra (CD).